Forskolin is a weight reduction and bodybuilding herb product, which has gained some attention on the market. It is on the other hand marketed as Colforsin and Coleonol as well. That is an organic and natural chemical substance derived from the tuberous roots of Indian Coleus plant. It seems to have gained some awareness after it was showcased by Dr Oz in one of his shows.
Indian Coleus plant has been used for therapeutic purposes for centuries. Since part of Ayurvedic medicine(Ancient Indian medicine) tradition it was used for managing various heart conditions including high blood pressure, upper body pain(angina), painful urination, convulsions and respiratory disorders such as asthma.
Unfortunately very little science went at the rear of the modern day claims about medicinal great things about this herb. It seems like today's opportunistic marketers do not care about thorough research but start drumming upward their campaigns at slightest hints of what may be remotely effective.
To be able to get back to the purpose, there was only one peer reviewed scientific research done about Forskolin which was published in scientific journal. This study showed significant effects on overweight and obese men. That reduced body fat portion and body fat size. It also increased slim bone mass and serum testosterone levels in over weight and obese men. A single should take notice that study was conducted only on men! Just one scientific study is obviously not sufficient enough to establish credibility of a supplement product.
Forskolin activates enzyme adenylyl cyclase. This chemical is involved in transmitting chemicals signals from outside of a cell, through mobile membrane to the inside of a cell. Subsequent result is increased level of chemical messenger called cyclic AMP(Adenosine monophosphate) or cAMP in short. cAMP is an important messenger in many biological processes. It is accountable for transferring effects of human hormones like adrenaline, which cannot pass through the mobile membranes, to inside of the cell. Subsequently it plays role in rules of glycogen, sugar and lipid metabolism. It is believed, for this reason activation system, it may be playing role in decreasing body fat and increasing lean bone bulk.
Although fat loss and lean bone mass increasing results have not been researched that extensively, one of the well observed effect of Forskolin is that as a vasodilator and bronchodilator. It has recently been regularly observed to minimize blood vessels pressure. It has recently been observed to work at decreasing asthma attacks. Given this, one needs to be careful, when using it as a weight loss supplement, because of you take blood pressure reducing medicines like calcium channel blockers or beta blockers, Forskolin works in combination with those medicine and there will be ingredient effect of reduction in bloodstream pressure and it could turn into a serious issues. Just as high blood pressure is not good, a significantly low blood pressure is not good either.
In laboratory studies in test-tubes an on animals it has been observed that Forskolin interacts with melanin under skin and resulting result is that of sun tanning! Don't be surprised if it is claimed that the same miracle medication will loose weight, help build body and will do tanning at the same time without heading to the sun!!